I-Angioedema iyisondo elijule kakhulu lesikhumba. Ngenkathi esimweni sesifuba kuvela uketshezi oluvela emikhunjini engaphansi nje kwesikhumba, "ukuvuza" ku-angioedema kusezingxenyeni zesikhumba ezijulile.

I-Angioedema (i-angio = isitsha, i-oedoema = ukugcinwa kwamanzi ezicutshini) ibonakala nge:

  • ukuvuvukala okungazelelwe, okunzima kwezingqimba ezijulile zesikhumba
  • ngezinye izikhathi ubuhlungu, okungajwayelekile ukulunywa
  • ukubandakanyeka kaningi kolwelwesi lwamafinyila - ukubuyela emuva okuhlala isikhathi eside kuze kufike emahoreni angama-72 kunangesifuba

Isigaxa esivelayo sinomphetho ongagqamile kangako futhi ngokuvamile asihlukani nesikhumba esijwayelekile ngombala. I-Angioedema ivame ukuvela ebusweni, ikakhulukazi eduze kwamehlo nasezindebeni, nasezandleni nasezinyaweni. Iningi lokuvuvukala ngomqondo obanzi lihlobene nokungezwani komzimba futhi liqondiswa yi-neurotransmitter histamine. Kepha kunezinye izimbangela, ezingezwani ne-non-histamine-mediated of isikhumba nokuvuvukala kwe-mucosal.